Issue 10, 2016
From the journal:

RSC Advances

Time evolution and dynamic cellular uptake of PEGYlated gold nanorods†

Hongyuan Song,‡a   Qingqiang Xu,‡b   Hongwei Di,b   Ting Guo,a   Zhongtian Qi*b  and  Shihong Zhao*a  

* Corresponding authors

a Department of Ophthalmology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
E-mail: zhaosh@smmu.edu.cn

b Department of Microbiology, Second Military Medical University, Shanghai 200433, China
E-mail: qizt@smmu.edu.cn

Abstract

The protein corona formed and evolved when PEGYlated gold nanorods (GNRs) are cultured with cells. The changes of protein corona alter nanorods characteristics significantly which results in dynamic cellular uptake pathways. This dynamic nature should be well considerded for future applications and the prevention of data misinterpretation.

Graphical abstract: Time evolution and dynamic cellular uptake of PEGYlated gold nanorods

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Article information

DOI
https://doi.org/10.1039/C5RA24460A
Article type
Communication
Submitted
19 Nov 2015
Accepted
11 Jan 2016
First published
14 Jan 2016

RSC Adv., 2016,6, 8089-8092

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Time evolution and dynamic cellular uptake of PEGYlated gold nanorods

H. Song, Q. Xu, H. Di, T. Guo, Z. Qi and S. Zhao, RSC Adv., 2016, 6, 8089 DOI: 10.1039/C5RA24460A

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