Issue 23, 2016

Microwave-assisted regioselective sulfenylation of indoles under solvent- and metal-free conditions

Abstract

Herein, we report a solvent- and metal-free methodology for the sulfenylation of indoles with sulfinic acids in the absence of an external catalyst under microwave irradiation. This environmentally friendly approach offered the desired products in moderate to excellent yields in only 10 min. Several functional group tolerances were monitored under the optimized conditions.

Graphical abstract: Microwave-assisted regioselective sulfenylation of indoles under solvent- and metal-free conditions

Supplementary files

Article information

Article type
Paper
Submitted
10 Dec 2015
Accepted
05 Feb 2016
First published
09 Feb 2016

RSC Adv., 2016,6, 18929-18935

Microwave-assisted regioselective sulfenylation of indoles under solvent- and metal-free conditions

R. Rahaman, N. Devi, J. R. Bhagawati and P. Barman, RSC Adv., 2016, 6, 18929 DOI: 10.1039/C5RA26425A

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