Issue 20, 2016
From the journal:

RSC Advances

CuI-catalyzed oxidative cross coupling of oximes with tetrahydrofuran: a direct access to O-tetrahydrofuran-2-yl oxime ethers†

Zhi-Hui Ren,*a   Mi-Na Zhaoa  and  Zheng-Hui Guan*a  

* Corresponding authors

a Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University, Xi'an 710127, P. R. China
E-mail: guanzhh@nwu.edu.cn, renzhh@nwu.edu.cn

Abstract

An efficient copper(I)-catalyzed oxidative tetrahydrofuranylation of oximes has been developed. This reaction shows good functional group tolerance and various substituted ketoximes and aldoximes coupled smoothly with THF to give the corresponding O-tetrahydrofuran-2-yl oxime ethers in high yields.

Graphical abstract: CuI-catalyzed oxidative cross coupling of oximes with tetrahydrofuran: a direct access to O-tetrahydrofuran-2-yl oxime ethers

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Article information

DOI
https://doi.org/10.1039/C5RA27899F
Article type
Communication
Submitted
28 Dec 2015
Accepted
04 Feb 2016
First published
05 Feb 2016

RSC Adv., 2016,6, 16516-16519

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CuI-catalyzed oxidative cross coupling of oximes with tetrahydrofuran: a direct access to O-tetrahydrofuran-2-yl oxime ethers

Z. Ren, M. Zhao and Z. Guan, RSC Adv., 2016, 6, 16516 DOI: 10.1039/C5RA27899F

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