Direct access to non-aromatic 1,2,3,6-tetrahydro-1,2,3,4-tetrazines via [4 + 2] cycloaddition of α-halogeno hydrazones with azodicarboxylic acid derivatives

Hong-Wu Zhao; Hai-Liang Pang; Bo Li; Ting Tian; Xiao-Qin Chen; Xiu-Qing Song; Wei Meng; Zhao Yang; Yue-Yang Liu; Yu-Di Zhao

doi:10.1039/C6RA01359G

Direct access to non-aromatic 1,2,3,6-tetrahydro-1,2,3,4-tetrazines via [4 + 2] cycloaddition of α-halogeno hydrazones with azodicarboxylic acid derivatives†

Hong-Wu Zhao,*^a Hai-Liang Pang,^a Bo Li,^a Ting Tian,^a Xiao-Qin Chen,^a Xiu-Qing Song,^a Wei Meng,^a Zhao Yang,^a Yue-Yang Liu^a and Yu-Di Zhao^a

Author affiliations

* Corresponding authors

^a College of Life Science and Bio-engineering, Beijing University of Technology, No. 100 Pingleyuan, Chaoyang District, Beijing 100124, P. R. China
E-mail: hwzhao@bjut.edu.cn

Abstract

In the presence of K₂CO₃, the [4 + 2] cycloaddition of α-halogeno hydrazones with azodicarboxylic acid derivatives proceeded efficiently, and delivered novel non-aromatic 1,2,3,6-tetrahydro-1,2,3,4-tetrazines in moderate to excellent chemical yields.

RSC Advances

Direct access to non-aromatic 1,2,3,6-tetrahydro-1,2,3,4-tetrazines via [4 + 2] cycloaddition of α-halogeno hydrazones with azodicarboxylic acid derivatives†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Direct access to non-aromatic 1,2,3,6-tetrahydro-1,2,3,4-tetrazines via [4 + 2] cycloaddition of α-halogeno hydrazones with azodicarboxylic acid derivatives

Social activity

Search articles by author

Spotlight

Advertisements