A method to prepare functionalized 2,3-dihydrofurans by Sc(OTf)3-catalyzed cyclization of α-allylated 1,3-dicarbonyl compounds is reported. The reactions were shown to be operationally simplistic and proceed efficiently for a variety of substrates, leading to the formation of 2,2-disubstituted 2,3-dihydrofurans in good to excellent yields.
Z. Cao, R. Zhang, X. Meng, H. Li, J. Li, H. Zhu, G. Chen, X. Sun and J. You, RSC Adv., 2016, 6, 74582 DOI: 10.1039/C6RA14051C
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