Issue 3, 2017
From the journal:

Chemical Communications

A simply triggered peptide-based hydrogel as an injectable nanocarrier of tanshinone IIA and tanshinones†

Yajun Yin,a   Can Wu,a   Junling Wang,a   Fengjuan Song,a   Wanqing Yue*ab  and  Wenying Zhong*ab  

* Corresponding authors

a Department of Analytical Chemistry, China Pharmaceutical University, Nanjing, China

b Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing 210009, P. R. China
E-mail: yuewq@cpu.edu.cn, wyzhong@cpu.edu.cn

Abstract

An easily self-assembled and gelated octa-peptide FHFDFHFD was chosen as a novel drug delivery system (DDS) for both tanshinone IIA and total tanshinone extract. The DDS showed increased loading capacity, sustained drug release and better anticancer capability. Our research proved that a hydrogel DDS of other traditional Chinese medicines is possible.

Graphical abstract: A simply triggered peptide-based hydrogel as an injectable nanocarrier of tanshinone IIA and tanshinones

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Article information

DOI
https://doi.org/10.1039/C6CC08502D
Article type
Communication
Submitted
22 Oct 2016
Accepted
30 Nov 2016
First published
30 Nov 2016

Chem. Commun., 2017,53, 529-532

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A simply triggered peptide-based hydrogel as an injectable nanocarrier of tanshinone IIA and tanshinones

Y. Yin, C. Wu, J. Wang, F. Song, W. Yue and W. Zhong, Chem. Commun., 2017, 53, 529 DOI: 10.1039/C6CC08502D

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