Issue 16, 2017

Programmable DNA triple-helix molecular switch in biosensing applications: from in homogenous solutions to in living cells

Abstract

Herein, we demonstrated a new gold nanoparticles (AuNPs)-integrated programmable triple-helix molecular switch (THMS) to realize the biosensing of multiple targets from in homogenous solution to in living cells. The results demonstrated that this proposed programmable THMS could be successfully used for imaging multiple messenger RNA (mRNA) in living cells and it significantly extends the scope of the THMS sensing platform.

Graphical abstract: Programmable DNA triple-helix molecular switch in biosensing applications: from in homogenous solutions to in living cells

Supplementary files

Article information

Article type
Communication
Submitted
29 Nov 2016
Accepted
20 Jan 2017
First published
20 Jan 2017

Chem. Commun., 2017,53, 2507-2510

Programmable DNA triple-helix molecular switch in biosensing applications: from in homogenous solutions to in living cells

P. Tang, J. Zheng, J. Tang, D. Ma, W. Xu, J. Li, Z. Cao and R. Yang, Chem. Commun., 2017, 53, 2507 DOI: 10.1039/C6CC09496A

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