Issue 27, 2017

Difluoromethylcarbene for iron-catalyzed cyclopropanation

Abstract

Difluoroethylsulfonium salt, Ph2S+CH2CF2H OTf, was developed into a convenient difluoromethylcarbene reagent for the iron-catalyzed cyclopropanation of terminal olefins, giving various difluoromethyl–cyclopropanes with excellent diastereoselectivities and in high yields.

Graphical abstract: Difluoromethylcarbene for iron-catalyzed cyclopropanation

Supplementary files

Article information

Article type
Communication
Submitted
02 Mar 2017
Accepted
13 Mar 2017
First published
13 Mar 2017

Chem. Commun., 2017,53, 3870-3873

Difluoromethylcarbene for iron-catalyzed cyclopropanation

Y. Duan, J. Lin, J. Xiao and Y. Gu, Chem. Commun., 2017, 53, 3870 DOI: 10.1039/C7CC01636K

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