Issue 63, 2017
From the journal:

Chemical Communications

A simple supramolecular assay for drug detection in urine†

Silvia Sonzini, ORCID logo a   Jade A. McCune,b   Peter Ravn,c   Oren A. Scherman ORCID logo *b  and  Christopher F. van der Walle ORCID logo *a  

* Corresponding authors

a Formulation Sciences, MedImmune Ltd, Granta Park, Cambridge CB21 6GH, UK
E-mail: wallec@medimmune.com

b Melville Laboratory for Polymer Synthesis, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK

c Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Cambridge CB21 6GH, UK

Abstract

A supramolecular colorimetric assay utilising the macrocyclic host cucurbit[7]uril (CB[7]) with a commercial dye molecule, neutral red (NR), was evaluated as a novel method for drug detection in urine of a model therapeutic peptide drug Octreotide.

Graphical abstract: A simple supramolecular assay for drug detection in urine

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Article information

DOI
https://doi.org/10.1039/C7CC04081D
Article type
Communication
Submitted
26 May 2017
Accepted
10 Jul 2017
First published
21 Jul 2017

Chem. Commun., 2017,53, 8842-8845

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A simple supramolecular assay for drug detection in urine

S. Sonzini, J. A. McCune, P. Ravn, O. A. Scherman and C. F. van der Walle, Chem. Commun., 2017, 53, 8842 DOI: 10.1039/C7CC04081D

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