Issue 61, 2017
From the journal:

Chemical Communications

Zinc-promoted cyclization of tosylhydrazones and 2-(dimethylamino)malononitrile: an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles†‡

Bang-Hong Zhang,a   Lin-Sheng Lei,a   Si-Zhan Liu,a   Xue-Qing Mou,a   Wei-Ting Liu,a   Shao-Hua Wang, ORCID logo *abc   Jie Wang,a   Wen Baoa  and  Kun Zhangb  

* Corresponding authors

a School of Pharmacy, Lanzhou University, Lanzhou 730000, P. R. China
E-mail: wangshh@lzu.edu.cn

b School of Chemical and Environmental Engineering, Wuyi University, Jiangmen 529020, P. R. China

c Key Laboratory of Drug Targeting and Drug Delivery System, Ministry of Education, Sichuan University, Chengdu, P. R. China

Abstract

A Zn(OTf)2-promoted cyclization reaction of tosylhydrazones with 2-(dimethylamino)malononitrile has been successfully developed providing an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles.

Graphical abstract: Zinc-promoted cyclization of tosylhydrazones and 2-(dimethylamino)malononitrile: an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C7CC04610C
Article type
Communication
Submitted
14 Jun 2017
Accepted
05 Jul 2017
First published
06 Jul 2017

Chem. Commun., 2017,53, 8545-8548

Permissions

Request permissions

Zinc-promoted cyclization of tosylhydrazones and 2-(dimethylamino)malononitrile: an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles

B. Zhang, L. Lei, S. Liu, X. Mou, W. Liu, S. Wang, J. Wang, W. Bao and K. Zhang, Chem. Commun., 2017, 53, 8545 DOI: 10.1039/C7CC04610C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements