We describe the first one-pot borylation/Suzuki–Miyaura sp2–sp3 cross-coupling between readily available aryl (pseudo)halides and activated alkyl chlorides. This method streamlines the synthesis of diaryl methanes, α-aryl carbonyls and allyl aryl compounds, substructures that are commonly found in life changing drug molecules.
L. Whitaker, H. Y. Harb and A. P. Pulis, Chem. Commun., 2017, 53, 9364 DOI: 10.1039/C7CC05037B
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