Issue 91, 2017
From the journal:

Chemical Communications

Modular synthesis of thirty lead-like scaffolds suitable for CNS drug discovery†

Joan Mayol-Llinàs, ORCID logo a   William Farnaby‡b  and  Adam Nelson ORCID logo *ac  

* Corresponding authors

a School of Chemistry, University of Leeds, UK
E-mail: a.s.nelson@leeds.ac.uk

b Takeda Cambridge, Unit 418, Cambridge Science Park, Milton Road, Cambridge, UK

c Astbury Centre for Structural Molecular Biology, University of Leeds, UK

Abstract

A modular synthetic approach was developed that yielded thirty diverse lead-like scaffolds suitable for CNS drug discovery.

Graphical abstract: Modular synthesis of thirty lead-like scaffolds suitable for CNS drug discovery

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C7CC06078E
Article type
Communication
Submitted
03 Aug 2017
Accepted
20 Sep 2017
First published
03 Nov 2017
This article is Open Access
Creative Commons BY license

Chem. Commun., 2017,53, 12345-12348

Permissions

Request permissions

Modular synthesis of thirty lead-like scaffolds suitable for CNS drug discovery

J. Mayol-Llinàs, W. Farnaby and A. Nelson, Chem. Commun., 2017, 53, 12345 DOI: 10.1039/C7CC06078E

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements