Issue 87, 2017

High stability of gold nanoparticles towards DNA modification and efficient hybridization via a surfactant-free peptide route

Abstract

With the assistance of peptides, a stable and highly efficient approach for the quick loading of thiol–DNA onto AuNPs is proposed with a high DNA utilization, which is generally applicable to specific DNA detection and diverse AuNP sizes. The maximum efficiency of hybridization reached 93% while the reaction time was shortened to 30 min.

Graphical abstract: High stability of gold nanoparticles towards DNA modification and efficient hybridization via a surfactant-free peptide route

Supplementary files

Article information

Article type
Communication
Submitted
31 Aug 2017
Accepted
03 Oct 2017
First published
09 Oct 2017

Chem. Commun., 2017,53, 11909-11912

High stability of gold nanoparticles towards DNA modification and efficient hybridization via a surfactant-free peptide route

X. Li, F. Feng, Z. Wu, Y. Liu, X. Zhou and J. Hu, Chem. Commun., 2017, 53, 11909 DOI: 10.1039/C7CC06827A

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