Issue 91, 2017
From the journal:

Chemical Communications

A new AgNC fluorescence regulation mechanism caused by coiled DNA and its applications in constructing molecular beacons with low background and large signal enhancement†

Weijun Zhouab  and  Shaojun Dong ORCID logo *ab  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, P. R. China
E-mail: dongsj@ciac.ac.cn

b Graduate School of the Chinese Academy of Sciences, Beijing, P. R. China

Abstract

Herein, we report a new fluorescence regulation mechanism of DNA-templated AgNCs caused by coiled DNA. Based on these phenomena, a novel dual fluorescent AgNC-MB with exponential signal enhancement and remarkably low background was developed. The AgNC-MB could effectively facilitate template design and avoid the disturbance caused by undesirable hybridization.

Graphical abstract: A new AgNC fluorescence regulation mechanism caused by coiled DNA and its applications in constructing molecular beacons with low background and large signal enhancement

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Article information

DOI
https://doi.org/10.1039/C7CC06872G
Article type
Communication
Submitted
02 Sep 2017
Accepted
24 Oct 2017
First published
24 Oct 2017

Chem. Commun., 2017,53, 12290-12293

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A new AgNC fluorescence regulation mechanism caused by coiled DNA and its applications in constructing molecular beacons with low background and large signal enhancement

W. Zhou and S. Dong, Chem. Commun., 2017, 53, 12290 DOI: 10.1039/C7CC06872G

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