A hydrophilic inorganic framework based on a sandwich polyoxometalate: unusual chemoselectivity for aldehydes/ketones with in situ generated hydroxylamine

Abstract

A hydrophilic inorganic porous catalyst was prepared via the hydrothermal method. The combination of [WZn₃(H₂O)₂(ZnW₉O₃₄)₂]¹²⁻ and Co(II) provides a synergistical catalytic way to promote oximation of aldehyde/ketone with in situ generated hydroxylamine that initially produces an oxime, which further either dehydrates into a nitrile or undergoes a Beckmann rearrangement to form an amide.