Proof-of-concept is shown for two-phase countercurrent flow on paper. The device consists of two paper layers, one of which has been modified with a sizing agent to be hydrophobic. The layers exhibit different wetting behavior for water and octanol. Both phases dominate wetting in one of the layers and can be made to move in different directions along the interface to achieve liquid–liquid extraction.
G. IJ. Salentijn, M. Grajewski and E. Verpoorte, Lab Chip, 2017, 17, 3401 DOI: 10.1039/C7LC00770A
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