Issue 10, 2017
From the journal:

Natural Product Reports

The importance of asking “how and why?” in natural product structure elucidation

Patrick D. Browna  and  Andrew L. Lawrence ORCID logo *a  

* Corresponding authors

a EaStCHEM School of Chemistry, University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburgh, UK
E-mail: a.lawrence@ed.ac.uk

Abstract

Covering: up to 2017

This review highlights why careful consideration of the biosynthetic origin (the how) and the biological function (the why) of a natural product can be so useful during the determination of its structure. Recent examples of structural reassignments inspired by biosynthetic and functional insights will be presented. This review will demonstrate the importance of viewing the origin, structure and function of a natural product as intertwined threads of a single story, best viewed as a whole rather than as discrete topics.

Graphical abstract: The importance of asking “how and why?” in natural product structure elucidation

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Article information

DOI
https://doi.org/10.1039/C7NP00025A
Article type
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Submitted
06 Apr 2017
First published
29 Aug 2017
This article is Open Access
Creative Commons BY license

Nat. Prod. Rep., 2017,34, 1193-1202

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The importance of asking “how and why?” in natural product structure elucidation

P. D. Brown and A. L. Lawrence, Nat. Prod. Rep., 2017, 34, 1193 DOI: 10.1039/C7NP00025A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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