Issue 25, 2017
From the journal:

Organic & Biomolecular Chemistry

Ag(i)-Catalyzed oxidative decarboxylation of difluoroacetates with activated alkenes to form difluorooxindoles†

Wen Wan, ORCID logo *a   Jialiang Li,a   Guobin Ma,a   Yunrong Chen,a   Haizhen Jiang,a   Hongmei Dengb  and  Jian Hao*ac  

* Corresponding authors

a Department of Chemistry, Innovative Drug Research Center, Shanghai University, China
E-mail: wanwen@shu.edu.cn, jhao@shu.edu.cn

b Laboratory of Microstructures, Shanghai University, China

c Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China

Abstract

A silver-catalyzed oxidative decarboxylative gem-difluoromethylenation of difluoroacetates with activated alkenes under mild reaction conditions has been developed. This radical cascade reaction provides a new method for the construction of a variety of gem-difluoromethylenated oxindoles.

Graphical abstract: Ag(i)-Catalyzed oxidative decarboxylation of difluoroacetates with activated alkenes to form difluorooxindoles

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C7OB00955K
Article type
Paper
Submitted
19 Apr 2017
Accepted
30 May 2017
First published
31 May 2017

Org. Biomol. Chem., 2017,15, 5308-5317

Permissions

Request permissions

Ag(I)-Catalyzed oxidative decarboxylation of difluoroacetates with activated alkenes to form difluorooxindoles

W. Wan, J. Li, G. Ma, Y. Chen, H. Jiang, H. Deng and J. Hao, Org. Biomol. Chem., 2017, 15, 5308 DOI: 10.1039/C7OB00955K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements