Issue 31, 2017
From the journal:

Organic & Biomolecular Chemistry

Stereoselective synthesis of the viridiofungin analogue NA808 from a chiral tetrahydrofuran-carboxylic acid†

Masatoshi Murakata ORCID logo *a  and  Takuma Ikedaa  

* Corresponding authors

a API Process Development Department, Chugai Pharmaceutical Co., Ltd., 5-5-1 Ukima, Kita-Ku, Tokyo 115-8543, Japan
E-mail: murakatamst@chugai-pharm.co.jp

Abstract

The viridiofungin analogue NA808 was synthesized by the stereoselective Ireland–Claisen rearrangement of dienylmethyl ester, regioselective bromolactonization of β-divinylpropanoic acid and retro-bromolactonization.

Graphical abstract: Stereoselective synthesis of the viridiofungin analogue NA808 from a chiral tetrahydrofuran-carboxylic acid

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C7OB01608E
Article type
Paper
Submitted
03 Jul 2017
Accepted
24 Jul 2017
First published
24 Jul 2017

Org. Biomol. Chem., 2017,15, 6632-6639

Permissions

Request permissions

Stereoselective synthesis of the viridiofungin analogue NA808 from a chiral tetrahydrofuran-carboxylic acid

M. Murakata and T. Ikeda, Org. Biomol. Chem., 2017, 15, 6632 DOI: 10.1039/C7OB01608E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements