Issue 19, 2017
From the journal:

Polymer Chemistry

Fine-tuning the pH response of polymersomes for mimicking and controlling the cell membrane functionality†

Hannes Gumz,abc   Thu Hang Lai,ad   Brigitte Voit*abc  and  Dietmar Appelhans ORCID logo *a  

* Corresponding authors

a Leibniz-Institut für Polymerforschung Dresden e.V., Hohe Straße 6, 01069 Dresden, Germany
E-mail: applhans@ipfdd.de, voit@ipfdd.de

b Organic Chemistry of Polymers, Technische Universität Dresden, 01062 Dresden, Germany

c Center for Advancing Electronics Dresden, 01062 Dresden, Germany

d Freie Universität Berlin, Department of Biochemistry and Organic Chemistry, Takustraße 3, 14195 Berlin, Germany

Abstract

To expand the biomedical applications of pH responsive polymersomes a concept is presented for precisely adjusting the pH triggered transition of the membrane permeability. The critical pH response value of the polymersomes could be shifted from acidic to neutral pH in a continuous manner by engineering the block copolymer compositions.

Graphical abstract: Fine-tuning the pH response of polymersomes for mimicking and controlling the cell membrane functionality

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Article information

DOI
https://doi.org/10.1039/C7PY00089H
Article type
Communication
Submitted
16 Jan 2017
Accepted
25 Apr 2017
First published
04 May 2017

Polym. Chem., 2017,8, 2904-2908

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Fine-tuning the pH response of polymersomes for mimicking and controlling the cell membrane functionality

H. Gumz, T. H. Lai, B. Voit and D. Appelhans, Polym. Chem., 2017, 8, 2904 DOI: 10.1039/C7PY00089H

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