Synthesis and ecotoxicological impact of ferrocene-derived amino-phosphonates using a battery of bioassays

Abstract

Due to the fact that α-aminophosphonates are structurally analogous to α-amino acids, the search for new biologically active agents based on the chemistry of these compounds has stimulated growing interest. Although there is increasing attention focused on the various applications of these compounds, there is poor information about their ecotoxicological impact on the environment. In this study, ferrocene-derived aminophosphonates have been synthesized and their environmental impact on selected plants, namely Avena sativa and Raphanus sativus as well as on the bacteria Vibrio fischeri, and the crustacean Heterocypris inconguens, has been assessed and their ecotoxicological profile determined.