A turn-on fluorescent formaldehyde probe regulated by combinational PET and ICT mechanisms for bioimaging applications†
Abstract
An illuminating formaldehyde-responsive fluorescence probe (Naph-FA) with a turn-on emission signal was rationally designed and synthesized. The reaction-based probe undergoes successive condensation, 2-aza-Cope rearrangement and hydrolysis processes in response to formaldehyde, and the fluorescence signal was regulated by combinational PET and ICT mechanisms.