Issue 11, 2018

A domain-based DNA circuit for smart single-nucleotide variant identification

Abstract

According to the differential information of four homologous oligonucleotides, two domain-based encoders have been constructed with the molecular information as the input. Based on the one-to-one correspondence between the input and output, SNVs can be identified and their sites can be located at the domain level.

Graphical abstract: A domain-based DNA circuit for smart single-nucleotide variant identification

Supplementary files

Article information

Article type
Communication
Submitted
05 Oct 2017
Accepted
17 Nov 2017
First published
17 Nov 2017

Chem. Commun., 2018,54, 1311-1314

A domain-based DNA circuit for smart single-nucleotide variant identification

W. Zhong, W. Tang, J. Fan, J. Zhang, X. Zhou and Y. Liu, Chem. Commun., 2018, 54, 1311 DOI: 10.1039/C7CC07733E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements