Issue 13, 2018

Evolutionary selection of personalized melanoma cell/tissue dual-homing peptides for guiding bionanofibers to malignant tumors

Abstract

Both melanoma cells and tissues were allowed to interact with an identical pool of billions of human-safe phage nanofiber clones with each genetically displaying a unique 12-mer peptide at the tips, respectively, resulting in the discovery of bionanofibers displaying a melanoma cell/tissue dual-homing peptide for personalized targeted melanoma therapy.

Graphical abstract: Evolutionary selection of personalized melanoma cell/tissue dual-homing peptides for guiding bionanofibers to malignant tumors

Supplementary files

Article information

Article type
Communication
Submitted
25 Nov 2017
Accepted
16 Jan 2018
First published
26 Jan 2018

Chem. Commun., 2018,54, 1631-1634

Evolutionary selection of personalized melanoma cell/tissue dual-homing peptides for guiding bionanofibers to malignant tumors

M. Yang, Y. Li, Y. Huai, C. Wang, W. Yi and C. Mao, Chem. Commun., 2018, 54, 1631 DOI: 10.1039/C7CC09077C

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