High quantum yield Ag2S quantum dot@polypeptide-engineered hybrid nanogels for targeted second near-infrared fluorescence/photoacoustic imaging and photothermal therapy

Dong-Hui Zhao; Jie Yang; Rui-Xue Xia; Ming-Hao Yao; Rui-Mei Jin; Yuan-Di Zhao; Bo Liu

doi:10.1039/C7CC09266K

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High quantum yield Ag₂S quantum dot@polypeptide-engineered hybrid nanogels for targeted second near-infrared fluorescence/photoacoustic imaging and photothermal therapy†

Dong-Hui Zhao,‡^a Jie Yang,‡^a Rui-Xue Xia,^a Ming-Hao Yao,^ab Rui-Mei Jin,^a Yuan-Di Zhao

*^ab and Bo Liu

*^ab

Author affiliations

* Corresponding authors

^a Britton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics – Hubei Bioinformatics & Molecular Imaging Key Laboratory, Collaborative Innovation Center for Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, Hubei, P. R. China
E-mail: zydi@mail.hust.edu.cn, lbyang@mail.hust.edu.cn

^b Key Laboratory of Biomedical Photonics (HUST), Ministry of Education, Huazhong University of Science and Technology, Wuhan 430074, Hubei, P. R. China

Abstract

A high quantum yield (4.3%) hybrid nanogel system based on engineered polypeptides and Ag₂S quantum dots has been developed as a multifunctional diagnostic and therapeutic agent for targeted second near-infrared fluorescence, photoacoustic imaging, and photothermal therapy.

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Article information

DOI: https://doi.org/10.1039/C7CC09266K
Article type: Communication
Submitted: 03 Dec 2017
Accepted: 08 Dec 2017
First published: 08 Dec 2017

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Chem. Commun., 2018,54, 527-530

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High quantum yield Ag₂S quantum dot@polypeptide-engineered hybrid nanogels for targeted second near-infrared fluorescence/photoacoustic imaging and photothermal therapy

D. Zhao, J. Yang, R. Xia, M. Yao, R. Jin, Y. Zhao and B. Liu, Chem. Commun., 2018, 54, 527 DOI: 10.1039/C7CC09266K

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Chemical Communications