Issue 30, 2018
From the journal:

Chemical Communications

Polysulfide-triggered fluorescent indicator suitable for super-resolution microscopy and application in imaging†

Anila Hoskere A.,a   Sreejesh Sreedharan,b   Firoj Ali,a   Carl G. Smythe,c   Jim A. Thomas ORCID logo *b  and  Amitava Das ORCID logo *ad  

* Corresponding authors

a Organic Chemistry Division, CSIR-National Chemical Laboratory, Pune-411008, India

b Department of Chemistry, University of Sheffield, Sheffield, UK
E-mail: james.thomas@sheffield.ac.uk

c Department of Biomedical Science, University of Sheffield, Sheffield, UK

d CSIR-Central Salt & Marine Chemicals Research Institute, Bhavnagar 364002, Gujarat, India
E-mail: a.das@csmcri.res.in

Abstract

A new physiologically benign and cell membrane permeable BODIPY based molecular probe, MB-Sn, specifically senses intracellular hydrogen polysulfides (H2Sn, n > 1) localized in the endoplasmic reticulum. This reagent is suitable for mapping the intracellular distribution of H2Sn by wide-field as well as super-resolution Structured Illumination Microscopy (SIM).

Graphical abstract: Polysulfide-triggered fluorescent indicator suitable for super-resolution microscopy and application in imaging

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Article information

DOI
https://doi.org/10.1039/C8CC01332B
Article type
Communication
Submitted
15 Feb 2018
Accepted
19 Mar 2018
First published
20 Mar 2018

Chem. Commun., 2018,54, 3735-3738

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Polysulfide-triggered fluorescent indicator suitable for super-resolution microscopy and application in imaging

A. H. A., S. Sreedharan, F. Ali, C. G. Smythe, J. A. Thomas and A. Das, Chem. Commun., 2018, 54, 3735 DOI: 10.1039/C8CC01332B

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