Issue 44, 2018
From the journal:

Chemical Communications

Photochemical reductive homologation of hydrogen cyanide using sulfite and ferrocyanide†

Jianfeng Xu,a   Dougal J. Ritson,a   Sukrit Ranjan,b   Zoe R. Todd, ORCID logo b   Dimitar D. Sasselovb  and  John D. Sutherland*a  

* Corresponding authors

a MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, UK
E-mail: johns@mrc-lmb.cam.ac.uk

b Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138, USA

Abstract

Photoredox cycling during UV irradiation of ferrocyanide ([FeII(CN)6]4−) in the presence of stoichiometric sulfite (SO32−) is shown to be an extremely effective way to drive the reductive homologation of hydrogen cyanide (HCN) to simple sugars and precursors of hydroxy acids and amino acids.

Graphical abstract: Photochemical reductive homologation of hydrogen cyanide using sulfite and ferrocyanide

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Article information

DOI
https://doi.org/10.1039/C8CC01499J
Article type
Communication
Submitted
23 Feb 2018
Accepted
07 Mar 2018
First published
15 May 2018
This article is Open Access
Creative Commons BY license

Chem. Commun., 2018,54, 5566-5569

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Photochemical reductive homologation of hydrogen cyanide using sulfite and ferrocyanide

J. Xu, D. J. Ritson, S. Ranjan, Z. R. Todd, D. D. Sasselov and J. D. Sutherland, Chem. Commun., 2018, 54, 5566 DOI: 10.1039/C8CC01499J

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