Paramagnetic nanoemulsions with unified signals for sensitive 19F MRI cell tracking

Qiaoli Peng; Yu Li; Shaowei Bo; Yaping Yuan; Zhigang Yang; Shizhen Chen; Xin Zhou; Zhong-Xing Jiang

doi:10.1039/C8CC02938E

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Paramagnetic nanoemulsions with unified signals for sensitive ¹⁹F MRI cell tracking†

Qiaoli Peng,^a Yu Li,^a Shaowei Bo,^a Yaping Yuan,^b Zhigang Yang,^b Shizhen Chen,^b Xin Zhou

^b and Zhong-Xing Jiang

*^a

Author affiliations

* Corresponding authors

^a Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals and School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China
E-mail: zxjiang@whu.edu.cn

^b State Key Laboratory for Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan 430071, China

Abstract

As a promising cell tracking technology, ¹⁹F MRI suffers from low sensitivity. Here, fluorinated nanoemulsions with a unified ¹⁹F signal and paramagnetic relaxation enhancement were developed as ¹⁹F MRI cellular tracers with high stability, size controllability, biocompatibility, cellular uptake, and dual-modality for sensitive in vivo RAW264.7 cell tracking.

Download options Please wait...

Supplementary files

Supplementary information PDF (2179K)

Article information

DOI: https://doi.org/10.1039/C8CC02938E
Article type: Communication
Submitted: 13 Apr 2018
Accepted: 16 May 2018
First published: 16 May 2018

Download Citation

Chem. Commun., 2018,54, 6000-6003

Permissions

Request permissions

Paramagnetic nanoemulsions with unified signals for sensitive ¹⁹F MRI cell tracking

Q. Peng, Y. Li, S. Bo, Y. Yuan, Z. Yang, S. Chen, X. Zhou and Z. Jiang, Chem. Commun., 2018, 54, 6000 DOI: 10.1039/C8CC02938E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications