We present an automated microscale flow chemistry platform for rapid performance evaluation of continuous and discrete reaction parameters in homogeneous hydroformylation reactions. We demonstrate the versatility of the developed microfluidic platform through a systematic study of the effects of a library of phosphine-based ligands on catalytic activity and regioselectivity.
C. Zhu, K. Raghuvanshi, C. W. Coley, D. Mason, J. Rodgers, M. E. Janka and M. Abolhasani, Chem. Commun., 2018, 54, 8567 DOI: 10.1039/C8CC04650F
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