A photocaged fluorescent probe for imaging hypochlorous acid in lysosomes

Mingguang Ren; Zihong Li; Jing Nie; Li Wang; Weiying Lin

doi:10.1039/C8CC04926B

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A photocaged fluorescent probe for imaging hypochlorous acid in lysosomes†

Mingguang Ren,

^a Zihong Li,^a Jing Nie,^b Li Wang^a and Weiying Lin

*^a

Author affiliations

* Corresponding authors

^a Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Shandong 250022, P. R. China
E-mail: weiyinglin2013@163.com

^b School of Chemical Engineering & Technology, China University of Mining and Technology, Xuzhou, Jiangsu, P. R. China

Abstract

By combining the advantages of the photocaging technology and traditional analyte-responsive fluorescent probes, we designed and synthesized the first photocaged lysosomal-targeted fluorescent HOCl probe (PL-HA). The new caged PL-HA probe was capable of remote light-controlled recognition of HOCl in lysosomes.

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Article information

DOI: https://doi.org/10.1039/C8CC04926B
Article type: Communication
Submitted: 20 Jun 2018
Accepted: 13 Jul 2018
First published: 18 Jul 2018

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Chem. Commun., 2018,54, 9238-9241

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A photocaged fluorescent probe for imaging hypochlorous acid in lysosomes

M. Ren, Z. Li, J. Nie, L. Wang and W. Lin, Chem. Commun., 2018, 54, 9238 DOI: 10.1039/C8CC04926B

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Chemical Communications

A photocaged fluorescent probe for imaging hypochlorous acid in lysosomes†

Abstract

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A photocaged fluorescent probe for imaging hypochlorous acid in lysosomes

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