Issue 82, 2018
From the journal:

Chemical Communications

Co-assembling FRET nanomedicine with self-indicating drug release†

Yang Li,‡a   Jiao Zhu,‡b   Tianyi Kang,a   Yuwen Chen,a   Yu Liu,a   Yulan Huang,a   Yi Luo,ac   Meijuan Huangb  and  Maling Gou ORCID logo *a  

* Corresponding authors

a Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China
E-mail: goumaling@scu.edu.cn

b Department of Thoracic Oncology, Cancer Center, West China Hospital, Medical School, Sichuan University, Chengdu, China

c Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, China

Abstract

Two lipophilic fluorescent prodrugs co-assembled into nanoaggregates with the ability to release FRET-indicated drugs, which was used to investigate the role of reduction-responsive linkers on drug release kinetics in the cytoplasm and physiologically relevant media in a visualized, noninvasive manner.

Graphical abstract: Co-assembling FRET nanomedicine with self-indicating drug release

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Article information

DOI
https://doi.org/10.1039/C8CC06792A
Article type
Communication
Submitted
21 Aug 2018
Accepted
18 Sep 2018
First published
20 Sep 2018

Chem. Commun., 2018,54, 11618-11621

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Co-assembling FRET nanomedicine with self-indicating drug release

Y. Li, J. Zhu, T. Kang, Y. Chen, Y. Liu, Y. Huang, Y. Luo, M. Huang and M. Gou, Chem. Commun., 2018, 54, 11618 DOI: 10.1039/C8CC06792A

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