Issue 97, 2018
From the journal:

Chemical Communications

A simple lateral flow biosensor for rapid detection of lead(ii) ions based on G-quadruplex structure-switching†

Dou Wang,‡ab   Chenchen Ge,‡ab   Kongpeng Lv,ab   Qingshuang Zou,ab   Quan Liu,ab   Liping Liu,*a   Qinhe Yang*bc  and  Shiyun Bao ORCID logo *a  

* Corresponding authors

a Department of Hepatobiliary and Pancreatic Surgery, The 2nd Clinical medicine College (Shenzhen People's Hospital) of Jinan University, Shenzhen 518020, China
E-mail: baomi94@163.com

b Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University, Guangzhou 510632, China

c School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China

Abstract

A novel lateral flow biosensor for rapid detection of Pb2+ was established for the first time based on Pb2+-induced G-quadruplex structure-switching. Semi-quantitative results could be read by reference to a colorimetric card. The whole process only took 15 minutes with a visual detection limit of 25 nM.

Graphical abstract: A simple lateral flow biosensor for rapid detection of lead(ii) ions based on G-quadruplex structure-switching

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Article information

DOI
https://doi.org/10.1039/C8CC06810K
Article type
Communication
Submitted
22 Aug 2018
Accepted
05 Nov 2018
First published
09 Nov 2018

Chem. Commun., 2018,54, 13718-13721

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A simple lateral flow biosensor for rapid detection of lead(II) ions based on G-quadruplex structure-switching

D. Wang, C. Ge, K. Lv, Q. Zou, Q. Liu, L. Liu, Q. Yang and S. Bao, Chem. Commun., 2018, 54, 13718 DOI: 10.1039/C8CC06810K

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