Issue 79, 2018
From the journal:

Chemical Communications

Aggregation-induced near-infrared emitting platinum(ii) terpyridyl complex: cellular characterisation and lysosome-specific localisation†

Jiatao Wu, ORCID logo ab   Yaqiong Li,c   Chunyan Tan, ORCID logo de   Xin Wang, ORCID logo a   Youming Zhang,ab   Jun Song, ORCID logo *a   Junle Qu ORCID logo *a  and  Wai-Yeung Wong ORCID logo *ab  

* Corresponding authors

a Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, P. R. China
E-mail: songjun@szu.edu.cn, jlqu@szu.edu.cn

b Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, P. R. China
E-mail: wai-yeung.wong@polyu.edu.hk

c Shijiazhuang People's Medical College, Shijiazhuang 050091, P. R. China

d Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China

e The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, P. R. China

Abstract

A novel near-infrared luminogen (TPE/TPY-Pt-PA/PEG) based on the terpyridyl Pt(II) complex with a tetraphenylethene periphery is synthesised and characterised. It displays aggregation-induced emission with the formation of self-assembled nanostructures. The nanoparticles fabricated with TPE/TPY-Pt-PA/PEG show excellent biocompatibility with high specificity to lysosomes in HeLa cells.

Graphical abstract: Aggregation-induced near-infrared emitting platinum(ii) terpyridyl complex: cellular characterisation and lysosome-specific localisation

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Article information

DOI
https://doi.org/10.1039/C8CC06839A
Article type
Communication
Submitted
22 Aug 2018
Accepted
07 Sep 2018
First published
10 Sep 2018

Chem. Commun., 2018,54, 11144-11147

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Aggregation-induced near-infrared emitting platinum(II) terpyridyl complex: cellular characterisation and lysosome-specific localisation

J. Wu, Y. Li, C. Tan, X. Wang, Y. Zhang, J. Song, J. Qu and W. Wong, Chem. Commun., 2018, 54, 11144 DOI: 10.1039/C8CC06839A

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