Diazachlorin and diazabacteriochlorin for one- and two-photon photodynamic therapy

Jean-François Longevial; Ayaka Yamaji; Dina Aggad; Gakhyun Kim; Wen Xi Chia; Tsubasa Nishimura; Yoshihiro Miyake; Sébastien Clément; Juwon Oh; Morgane Daurat; Christophe Nguyen; Dongho Kim; Magali Gary-Bobo; Sébastien Richeter; Hiroshi Shinokubo

doi:10.1039/C8CC07489E

Diazachlorin and diazabacteriochlorin for one- and two-photon photodynamic therapy†

Jean-François Longevial,

‡^ab Ayaka Yamaji,‡^a Dina Aggad,

‡^c Gakhyun Kim,‡^d Wen Xi Chia,^a Tsubasa Nishimura,^a Yoshihiro Miyake,

^a Sébastien Clément,

^b Juwon Oh,^d Morgane Daurat,

^c Christophe Nguyen,

^c Dongho Kim,

*^d Magali Gary-Bobo,

*^c Sébastien Richeter

*^b and Hiroshi Shinokubo

*^a

Author affiliations

* Corresponding authors

^a Department of Molecular and Macromolecular Chemistry, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan
E-mail: hshino@chembio.nagoya-u.ac.jp

^b Institut Charles Gerhardt de Montpellier, UMR 5253 CNRS-ENSCM-UM, 34095 Montpellier Cedex 05, France
E-mail: sebastien.richeter@umontpellier.fr

^c Institut des Biomolécules Max Mousseron, UMR 5247 CNRS-UM, 34093 Montpellier Cedex 05, France
E-mail: magali.gary-bobo@inserm.fr

^d Spectroscopy Laboratory for Functional π-Electronic Systems and Department of Chemistry, Yonsei University, Seoul 03722, Korea
E-mail: dongho@yonsei.ac.kr

Abstract

Diazachlorin and diazabacteriochlorin have been prepared through reduction of diazaporphyrin and their in vitro and in vivo activity in photodynamic therapy has been investigated.

Chemical Communications

Diazachlorin and diazabacteriochlorin for one- and two-photon photodynamic therapy†

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Diazachlorin and diazabacteriochlorin for one- and two-photon photodynamic therapy

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