Issue 95, 2018

Cell membrane camouflaged magnetic nanoparticles as a biomimetic drug discovery platform

Abstract

We report a novel biomimetic drug discovery platform using high expression epidermal growth factor receptor (EGFR) HEK 293 cell membrane camouflaged magnetic nanoparticles. The EGFR/magnetic cell membrane nanoparticles (MCMNs) integrated desirable magnetic features and special binding bioaffinity. Application of this drug-targeting concept is expected to pave ways to a new drug discovery strategy.

Graphical abstract: Cell membrane camouflaged magnetic nanoparticles as a biomimetic drug discovery platform

Supplementary files

Article information

Article type
Communication
Submitted
25 Oct 2018
Accepted
06 Nov 2018
First published
06 Nov 2018

Chem. Commun., 2018,54, 13427-13430

Cell membrane camouflaged magnetic nanoparticles as a biomimetic drug discovery platform

Y. Bu, Q. Hu, R. Ke, Y. Sui, X. Xie and S. Wang, Chem. Commun., 2018, 54, 13427 DOI: 10.1039/C8CC08530G

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