Fabrication of injectable CuS nanocomposite hydrogels based on UCST-type polysaccharides for NIR-triggered chemo-photothermal therapy

Yueyuan Zheng; Yuqing Liang; Depan Zhang; Zhijun Zhou; Juan Li; Xiaoyi Sun; You-Nian Liu

doi:10.1039/C8CC08785G

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Fabrication of injectable CuS nanocomposite hydrogels based on UCST-type polysaccharides for NIR-triggered chemo-photothermal therapy†

Yueyuan Zheng,‡^a Yuqing Liang,‡^a Depan Zhang,^a Zhijun Zhou,^b Juan Li,

*^a Xiaoyi Sun

*^a and You-Nian Liu

Author affiliations

* Corresponding authors

^a College of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan Province 410083, P. R. China
E-mail: juanli@csu.edu.cn, xiaoyisun@csu.edu.cn

^b Department of Laboratory Animals, Central South University, Changsha, Hunan Province 410083, P. R. China

Abstract

Injectable nanocomposite hydrogels containing small copper sulfide nanoparticles (6–8 nm) with a 54.6% photothermal conversion efficiency have been facilely prepared by applying an upper critical solution temperature (UCST)-type biopolymer gellan. This minimally invasive formulation ablates cancer completely in vivo after NIR-triggered chemo-photothermal therapy.

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Article information

DOI: https://doi.org/10.1039/C8CC08785G
Article type: Communication
Submitted: 04 Nov 2018
Accepted: 14 Nov 2018
First published: 14 Nov 2018

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Chem. Commun., 2018,54, 13805-13808

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Fabrication of injectable CuS nanocomposite hydrogels based on UCST-type polysaccharides for NIR-triggered chemo-photothermal therapy

Y. Zheng, Y. Liang, D. Zhang, Z. Zhou, J. Li, X. Sun and Y. Liu, Chem. Commun., 2018, 54, 13805 DOI: 10.1039/C8CC08785G

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Chemical Communications

Fabrication of injectable CuS nanocomposite hydrogels based on UCST-type polysaccharides for NIR-triggered chemo-photothermal therapy†

Abstract

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Fabrication of injectable CuS nanocomposite hydrogels based on UCST-type polysaccharides for NIR-triggered chemo-photothermal therapy

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