Issue 15, 2018

SURMOF induced polymorphism and crystal morphological engineering of acetaminophen polymorphs: advantage of heterogeneous nucleation

Abstract

Self-assembled monolayers are extended to SURMOFs as template hetero surfaces using a basic HKUST-1 MOF. The concept of MOF induced polymorphism with morphological engineering adapted to crystal engineering has shown to have the advantage of heterogeneous nucleation. The substrates are used to study the nucleation and growth of acetaminophen, and have resulted in metastable polymorphs which are of a desirable form with block morphology.

Graphical abstract: SURMOF induced polymorphism and crystal morphological engineering of acetaminophen polymorphs: advantage of heterogeneous nucleation

Supplementary files

Article information

Article type
Communication
Submitted
19 Feb 2018
Accepted
13 Mar 2018
First published
14 Mar 2018
This article is Open Access
Creative Commons BY license

CrystEngComm, 2018,20, 2084-2088

SURMOF induced polymorphism and crystal morphological engineering of acetaminophen polymorphs: advantage of heterogeneous nucleation

G. Bolla and A. S. Myerson, CrystEngComm, 2018, 20, 2084 DOI: 10.1039/C8CE00272J

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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