Au3Cu tetrapod nanocrystals: highly efficient and metabolizable multimodality imaging-guided NIR-II photothermal agents

Zhiyi Wang; Yanmin Ju; Shiyan Tong; Hongchen Zhang; Jian Lin; Baodui Wang; Yanglong Hou

doi:10.1039/C8NH00135A

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Au₃Cu tetrapod nanocrystals: highly efficient and metabolizable multimodality imaging-guided NIR-II photothermal agents†

Zhiyi Wang,‡^ab Yanmin Ju,‡^ca Shiyan Tong,^a Hongchen Zhang,^a Jian Lin,^d Baodui Wang

*^b and Yanglong Hou

*^a

Author affiliations

* Corresponding authors

^a Beijing Key Laboratory for Magnetoelectric Materials and Devices, Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing Innovation Centre for Engineering Science and Advanced Technology, Beijing 100871, China
E-mail: hou@pku.edu.cn

^b State Key Laboratory of Applied Organic Chemistry and Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and, Lanzhou University, Lanzhou, Gansu, China
E-mail: wangbd@lzu.edu.cn

^c College of Life Science, Peking University, Beijing 100871, China

^d Synthetic and Functional Biomolecules Center, Department of Chemical Biology, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China

Abstract

Gold and gold-based alloy nanocrystals (NCs) have been widely used in the field of photothermal therapy (PTT). However, the synthesis of multimodal nano-agents for precise and efficient PTT in the second near infrared (NIR-II) region remains a great challenge. Herein, Au₃Cu TPNCs were developed as a powerful platform for multimodal image-guided photothermal therapy with significant therapeutic effects and good metabolizability in the NIR-II region.

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Article information

DOI: https://doi.org/10.1039/C8NH00135A
Article type: Communication
Submitted: 12 Jun 2018
Accepted: 09 Jul 2018
First published: 10 Jul 2018

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Nanoscale Horiz., 2018,3, 624-631

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Au₃Cu tetrapod nanocrystals: highly efficient and metabolizable multimodality imaging-guided NIR-II photothermal agents

Z. Wang, Y. Ju, S. Tong, H. Zhang, J. Lin, B. Wang and Y. Hou, Nanoscale Horiz., 2018, 3, 624 DOI: 10.1039/C8NH00135A

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