Issue 33, 2018
From the journal:

Nanoscale

In situ gold nanoparticle growth on polydopamine-coated 3D-printed scaffolds improves osteogenic differentiation for bone tissue engineering applications: in vitro and in vivo studies†

Sang Jin Lee, ORCID logo ab   Hyo-Jung Lee,c   Sung-Yeol Kim,c   Ji Min Seok, ORCID logo a   Jun Hee Lee,a   Wan Doo Kim,a   Il Keun Kwon, ORCID logo b   Shin-Young Park‡*cd  and  Su A Park ORCID logo ‡*a  

* Corresponding authors

a Department of Nature-Inspired Nanoconvergence Systems, Korea Institute of Machinery and Materials, 156 Gajeongbuk-ro, Yuseong-gu, Daejeon 34103, Republic of Korea
E-mail: psa@kimm.re.kr

b Department of Dental Materials, School of Dentistry, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea

c Department of Periodontology, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam-si 13620, Republic of Korea
E-mail: nalby@hanmail.net

d Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul 03080, Republic of Korea

Abstract

In this study, we designed scaffolds coated with gold nanoparticles (GNPs) grown on a polydopamine (PDA) coating of a three-dimensional (3D) printed polycaprolactone (PCL) scaffold. Our results demonstrated that the scaffolds developed here may represent an innovative paradigm in bone tissue engineering by inducing osteogenesis as a means of remodeling and healing bone defects.

Graphical abstract: In situ gold nanoparticle growth on polydopamine-coated 3D-printed scaffolds improves osteogenic differentiation for bone tissue engineering applications: in vitro and in vivo studies

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Article information

DOI
https://doi.org/10.1039/C8NR04037K
Article type
Communication
Submitted
18 May 2018
Accepted
14 Jul 2018
First published
30 Jul 2018

Nanoscale, 2018,10, 15447-15453

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In situ gold nanoparticle growth on polydopamine-coated 3D-printed scaffolds improves osteogenic differentiation for bone tissue engineering applications: in vitro and in vivo studies

S. J. Lee, H. Lee, S. Kim, J. M. Seok, J. H. Lee, W. D. Kim, I. K. Kwon, S. Park and S. A. Park, Nanoscale, 2018, 10, 15447 DOI: 10.1039/C8NR04037K

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