Issue 39, 2018
From the journal:

Organic & Biomolecular Chemistry

A pendant peptide endows a sunscreen with water-resistance†

Aubrey J. Ellisona  and  Ronald T. Raines ORCID logo *abc  

* Corresponding authors

a Department of Chemistry, University of Wisconsin–Madison, 1101 University Avenue, Madison, WI 53706, USA

b Department of Biochemistry, University of Wisconsin–Madison, 433 Babcock Drive, Madison, WI 53706, USA

c Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
E-mail: rtraines@mit.edu

Abstract

Ultraviolet light causes skin cancer. Salicylic acid and other molecular filters absorb damaging radiation but are washed away readily. Conjugation to a collagen mimetic peptide is shown to retain salicylic acid on collagen-containing skin surrogates after repeated washing. This strategy, which is highly modular, could enhance the water-resistance of sunscreens.

Graphical abstract: A pendant peptide endows a sunscreen with water-resistance

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Article information

DOI
https://doi.org/10.1039/C8OB01773E
Article type
Communication
Submitted
24 Jul 2018
Accepted
10 Sep 2018
First published
10 Sep 2018
This article is Open Access
Creative Commons BY-NC license

Org. Biomol. Chem., 2018,16, 7139-7142

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A pendant peptide endows a sunscreen with water-resistance

A. J. Ellison and R. T. Raines, Org. Biomol. Chem., 2018, 16, 7139 DOI: 10.1039/C8OB01773E

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