Issue 1, 2018
From the journal:

Organic Chemistry Frontiers

Cu-Catalyzed tertiary alkylation of α-(trifluoromethyl)styrenes with tertiary alkylmagnesium reagents†

Wenpeng Dai,a   Yingyin Lin,a   Yan Wana  and  Song Cao ORCID logo *a  

* Corresponding authors

a Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology (ECUST), Shanghai 200237, China
E-mail: scao@ecust.edu.cn

Abstract

A novel and efficient method for the synthesis of 3-tertiary alkylated 1,1-difluorostyrene derivatives via Cu-catalyzed alkylation of α-(trifluoromethyl)styrenes with tertiary alkylmagnesium reagents at room temperature was developed.

Graphical abstract: Cu-Catalyzed tertiary alkylation of α-(trifluoromethyl)styrenes with tertiary alkylmagnesium reagents

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C7QO00716G
Article type
Research Article
Submitted
13 Aug 2017
Accepted
17 Sep 2017
First published
18 Sep 2017

Org. Chem. Front., 2018,5, 55-58

Permissions

Request permissions

Cu-Catalyzed tertiary alkylation of α-(trifluoromethyl)styrenes with tertiary alkylmagnesium reagents

W. Dai, Y. Lin, Y. Wan and S. Cao, Org. Chem. Front., 2018, 5, 55 DOI: 10.1039/C7QO00716G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements