Issue 7, 2018
From the journal:

Organic Chemistry Frontiers

A silver-catalyzed three-component reaction via stabilized cation: synthesis of polysubstituted tetrahydronaphthols and tetrahydronaphthylamines†

Hejiang Luo,a   Renxiao Liang,a   Lianfen Chen, ORCID logo *a   Huanfeng Jiang ORCID logo a  and  Shifa Zhu ORCID logo *a  

* Corresponding authors

a Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, P. R. China
E-mail: chenlf@scut.edu.cn, zhusf@scut.edu.cn

Abstract

An efficient and stereoselective method for the synthesis of polysubstituted tetrahydronaphthols and tetrahydronaphthylamines through a silver-catalyzed three-component reaction of enynals/enynimines, alkenes and H2O via a stabilized cation intermediate has been developed.

Graphical abstract: A silver-catalyzed three-component reaction via stabilized cation: synthesis of polysubstituted tetrahydronaphthols and tetrahydronaphthylamines

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Article information

DOI
https://doi.org/10.1039/C7QO01122A
Article type
Research Article
Submitted
16 Dec 2017
Accepted
23 Jan 2018
First published
24 Jan 2018

Org. Chem. Front., 2018,5, 1160-1164

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A silver-catalyzed three-component reaction via stabilized cation: synthesis of polysubstituted tetrahydronaphthols and tetrahydronaphthylamines

H. Luo, R. Liang, L. Chen, H. Jiang and S. Zhu, Org. Chem. Front., 2018, 5, 1160 DOI: 10.1039/C7QO01122A

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