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An efficient and straightforward protocol to complex indene-based polycyclic compounds via the cascade cyclization of propargylic alcohols and alkenes was developed. The catalyst FeCl3, as an Earth-abundant and environment friendly transition metal salt, is attractive. This reaction proceeded through unusual C–C bond cleavage.

Graphical abstract: A concise synthesis of indene-based polycyclic compounds via FeCl3-catalyzed cascade cyclization

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