Berberine-based carbon dots for selective and safe cancer theranostics

Fan Zhang; Ming Zhang; Xiao Zheng; Songyuan Tao; Zhanqiang Zhang; Madi Sun; Yubin Song; Jing Zhang; Dan Shao; Kan He; Jing Li; Bai Yang; Li Chen

doi:10.1039/C7RA12069A

Berberine-based carbon dots for selective and safe cancer theranostics†

Fan Zhang,‡^a Ming Zhang,‡^a Xiao Zheng,^a Songyuan Tao,^b Zhanqiang Zhang,^a Madi Sun,^a Yubin Song,^b Jing Zhang,^a Dan Shao,

*^a Kan He,^a Jing Li,^a Bai Yang

*^b and Li Chen*^ac

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* Corresponding authors

^a Department of Pharmacology, Nanomedicine Engineering Laboratory of Jilin Province, College of Basic Medical Sciences, Jilin University, Changchun 130021, China
E-mail: stanauagate@outlook.com, chenl@jlu.edu.cn

^b State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, P. R. China
E-mail: byangchem@jlu.edu.cn

^c School of Nursing, Jilin University, Changchun 130021, China

Abstract

Fluorescent berberine-based carbon dots (Ber–CDs) were prepared through a facile synthesis strategy. Ber–CDs exhibited excellent optical properties for bioimaging and retained the biofunctions of berberine, and enabled selective and safe anti-tumor performance, demonstrating their promising application potential in cancer theranostics.

RSC Advances

Berberine-based carbon dots for selective and safe cancer theranostics†

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