Visual synchronization of two 3-variable Lotka–Volterra oscillators based on DNA strand displacement

Abstract

DNA strand displacement as a theoretic foundation is helpful in constructing reaction networks and DNA circuits. Research on chemical kinetics is significant to exploit the inherent potential property of biomolecular systems. In this study, we investigated two typical reactions and designed DNA strands with a fluorophore and dark quencher for reaction networks using a 3-variable Lotka–Volterra oscillator system as an example to show the convenience of and superiority for observation of dynamic trajectory using our design, and took advantage of the synchronization reaction module to synchronize two 3-variable Lotka–Volterra oscillators. The classical theory of chemical reaction networks can be used to represent biological processes for mathematical modeling. We used this method to simulate the nonlinear kinetics of a 3-variable Lotka–Volterra oscillator system.