Issue 17, 2019

Dual-entropy-driven catalytic amplification reaction for ultra-sensitive and visible detection of Hg2+ in water based on thymine–Hg2+–thymine coordination chemistry

Abstract

An ultra-sensitive and visible Hg2+ detection strategy was established. It was based on T–Hg2+–T coordination chemistry and a dual-entropy-driven catalytic reaction (EDCR). The dual EDCR was initiated by T–Hg2+–T coordination chemistry, resulting in the release of a G-rich sequence to form a hemin/G-quadruplex-HRP-mimicking DNAzyme, and then catalyzing 3,3′,5,5′-tetramethylbenzidine (TMB) into TMB+, with a color change from colorless to blue. This method showed great sensitivity and excellent selectivity, and the limit of detection reached 0.6 pM. The feasibility of this method was demonstrated by real water samples. Moreover, the visible color change provided the possibility of ultra-sensitive detection of Hg2+ by the naked eye.

Graphical abstract: Dual-entropy-driven catalytic amplification reaction for ultra-sensitive and visible detection of Hg2+ in water based on thymine–Hg2+–thymine coordination chemistry

Supplementary files

Article information

Article type
Paper
Submitted
14 May 2019
Accepted
12 Jul 2019
First published
12 Jul 2019

Analyst, 2019,144, 5143-5149

Dual-entropy-driven catalytic amplification reaction for ultra-sensitive and visible detection of Hg2+ in water based on thymine–Hg2+–thymine coordination chemistry

Z. Xiong, Q. Liu, W. Yun, Y. Hu, X. Wang and L. Yang, Analyst, 2019, 144, 5143 DOI: 10.1039/C9AN00882A

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