A ratiometric two-photon fluorescent probe for the rapid detection of HClO in living systems

Li Wang; Mingguang Ren; Zihong Li; Lixuan Dai; Weiying Lin

doi:10.1039/C9AY00205G

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A ratiometric two-photon fluorescent probe for the rapid detection of HClO in living systems†

Li Wang,^a Mingguang Ren,

^a Zihong Li,^a Lixuan Dai^a and Weiying Lin

*^a

Author affiliations

* Corresponding authors

^a Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Jinan, Shandong 250022, P. R. China
E-mail: weiyinglin2013@163.com

Abstract

We have developed a ratiometric two-photon fluorescent probe: CR-HA. The CR-HA probe could be used for the determination of hypochlorous acid (HClO) in living systems. The result of fluorescence imaging showed that it could be used as a probe to image exogenous/endogenous HClO in living cells, and to detect HClO in living tissue and zebrafish.

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Article information

DOI: https://doi.org/10.1039/C9AY00205G
Article type: Communication
Submitted: 26 Jan 2019
Accepted: 22 Feb 2019
First published: 25 Feb 2019

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Anal. Methods, 2019,11, 1580-1584

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A ratiometric two-photon fluorescent probe for the rapid detection of HClO in living systems

L. Wang, M. Ren, Z. Li, L. Dai and W. Lin, Anal. Methods, 2019, 11, 1580 DOI: 10.1039/C9AY00205G

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Analytical Methods

A ratiometric two-photon fluorescent probe for the rapid detection of HClO in living systems†

Abstract

Supplementary files

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A ratiometric two-photon fluorescent probe for the rapid detection of HClO in living systems

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