Visible-light-induced Pd-catalyzed ortho-trifluoromethylation of acetanilides with CF3SO2Na under ambient conditions in the absence of an external photocatalyst†
Abstract
A visible-light-induced Pd-catalyzed ortho-trifluoromethylation of acetanilides with CF3SO2Na was developed. The reaction proceeded smoothly at room temperature in air without any external photocatalyst or additive, providing the desired products in moderate to good yields with good functional group tolerance and regioselectivity.