Issue 36, 2019

Size-controlled DNA-cross-linked hydrogel coated silica nanoparticles served as a ratiometric fluorescent probe for the detection of adenosine triphosphate in living cells

Abstract

Herein, we have designed a ratiometric fluorescent nanoprobe for adenosine triphosphate sensing and imaging in living cells, based on silica nanoparticles and a DNA-functionalized hybrid hydrogel. This ratiometric detecting method could validly avoid false-positive signals. Due to its controllable size, favorable biocompatibility and biostability, the nanohydrogel exhibited high cellular permeability and fast response in living cells.

Graphical abstract: Size-controlled DNA-cross-linked hydrogel coated silica nanoparticles served as a ratiometric fluorescent probe for the detection of adenosine triphosphate in living cells

Supplementary files

Article information

Article type
Communication
Submitted
12 Mar 2019
Accepted
05 Apr 2019
First published
05 Apr 2019

Chem. Commun., 2019,55, 5243-5246

Size-controlled DNA-cross-linked hydrogel coated silica nanoparticles served as a ratiometric fluorescent probe for the detection of adenosine triphosphate in living cells

X. Ji, J. Wang, S. Niu and C. Ding, Chem. Commun., 2019, 55, 5243 DOI: 10.1039/C9CC01832H

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