Issue 80, 2019
From the journal:

Chemical Communications

Single-stranded DNA designed lipophilic G-quadruplexes as transmembrane channels for switchable potassium transport†

Chunying Li,a   Hui Chen,a   Li Zhou,a   Hui Shi,a   Xiaoxiao He,a   Xiaohai Yang, ORCID logo *a   Kemin Wang ORCID logo a  and  Jianbo Liu ORCID logo *a  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, P. R. China
E-mail: liujianbo@hnu.edu.cn, yangxiaohai@hnu.edu.cn

Abstract

Single-stranded DNA designed G-quadruplexes, modified with lipophilic 12-carbon spacers and cholesterol to span lipid membranes, were developed as smart transmembrane channels for selective and switchable potassium ion (K+) transport across membranes.

Graphical abstract: Single-stranded DNA designed lipophilic G-quadruplexes as transmembrane channels for switchable potassium transport

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Article information

DOI
https://doi.org/10.1039/C9CC04176A
Article type
Communication
Submitted
30 May 2019
Accepted
30 Aug 2019
First published
30 Aug 2019

Chem. Commun., 2019,55, 12004-12007

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Single-stranded DNA designed lipophilic G-quadruplexes as transmembrane channels for switchable potassium transport

C. Li, H. Chen, L. Zhou, H. Shi, X. He, X. Yang, K. Wang and J. Liu, Chem. Commun., 2019, 55, 12004 DOI: 10.1039/C9CC04176A

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